Blastomycosis in dogs eyes.
Blastomycosis is a disease with worldwide distribution that is reported as common in North and Central America. It is caused by a dimorphic fungus of the order Mucorales. Little has been reported about its association with ocular diseases. We describe the clinical features, histopathological findings, and a successful treatment with voriconazole in dogs with unilateral uveitis and secondary retinal vasculitis. Blastomyces dermatitidis has been detected in the vitreous body of one dog by culture and polymerase chn reaction. Treatment was successful after 4 months with voriconazole, even though the dog was suffering from uveitis and secondary retinal vasculitis. Histopathological examination of the affected eyes revealed chronic granulomatous chorioretinitis, with evidence of retinal vasculitis and chorioretinitis. These cases highlight the potential zoonotic nature of blastomycosis and demonstrate the need for further studies to identify the risk factors for this disease. This is the first report of blastomycosis in dogs with ocular involvement. Blastomycosis may occur as a primary ocular disease and its prevalence is underestimated. This infection should be considered as a differential diagnosis in dogs with uveitis and secondary retinal vasculitis.